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Leadership

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Principal Investigator

Dave D'Alessio, M.D.

James B. Wyngaarden Distinguished Professor of Medicine

Dr. D'Alessio leads research in the regulation of glucose tolerance and food intake by gut hormones, with a focus on proglucagon peptides such as glucagon and GLP-1. He conducts clinical trials on new compounds for blood glucose control, weight loss, and vascular disease prevention, while also serving as Editor-in-Chief of the journal Diabetes and contributing to expert panels on diabetes care.

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Principal Investigator

Jon Campbell, PhD

Associate Professor of Medicine

Dr. Campbell researches the regulation of glucose and energy metabolism by gut-derived peptides like GLP-1 and GIP. His work explores the mechanisms through which these peptides influence beta- and alpha-cell function. Additionally, his research investigates the metabolic improvements observed with ligand receptor agonism, using genetic models to understand the independent effects on alpha to beta-cell function and weight loss. ​

Research Team

Dedication. Expertise. Passion.

Our research staff come from all over the world with a wide breadth of research experience. We pride ourselves on hard work, dedication, and our best efforts in leading change for obesity and diabetes.

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Senior Research Associate

Kimberley El, PhD

 

Dr. El's work focuses on the role of GIP receptors on pancreatic islets in response to agonism. She is eager to find counter regulatory mechanisms during insulin induced hypoglycemia in T1DM and T2DM patients. 

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Senior Research Associate

Sarah Hannou, PhD

Dr. Hannou's work looks into how obesity and diabetes is associated with metabolic diseases in the liver. Her focus is to uncover complex interplay between metabolic disorders and liver function aiming to uncover  underlying uses of diseases like non-alcoholic fatty liver disease (NAFLD). She enjoys spending time with her cat and going for long hikes.

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Research Associate

Hyunji Lee, PhD

Dr. Lee's work encompasses looking at different responses to GLP-1r agonism for mouse models with pancreatic beta-cell arrestin knockout conditions. She enjoys her time outside the lab building lego models and watching zombie movies.

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Postdoctoral Associate

Rashmita Basu, PhD

​Dr. Basu's work primarily focuses on investigating biased incretin signaling at the brain. She is also researching the molecular mechanism underlying incretin agonism versus antagonism. When not doing science, she loves to whip up new recipes or hiking scenic trails.

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Postdoctoral Associate

Brent Bachman, PhD

Dr. Bachman recently graduated from Purdue University, where he researched the effects of dietary saturated fat type on rodent models of high-fat diet-induced obesity. In his free time, he enjoys reading, running, and spending time with his wife and their dog and cat.

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Postdoctoral Associate

Nadya Morrow, PhD

Nadya completed her PhD training at the University of Ottawa in Canada, where she developed expertise in intestinal lipid metabolism. She is now focusing on uncovering the role of glucagon action in systemic water balance. Nadya loves playing sports, watching stand-up comedy, and following women's basketball!

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Postdoctoral Associate

Hannah Waterman, PhD

Dr. Waterman focuses on clinical studies of islet hormone regulation in insulin resistance and type 2 diabetes. Her work examines α- to β-cell communication, β-cell compensation during metabolic stress, and hepatic insulin sensitivity in humans. Outside of her research, she enjoys hiking and backpacking, reading books, and exploring new coffee shops.

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Laboratory Manager

Danielle Leander, B.S.

Ms. Leander focuses on glucose turnover and clamping research in freely moving mice, specializing in evaluating and interpreting data to provide analyses on progress, adverse trends, and recommendations. In addition, she manages mouse colonies, handling the importation and validation of mouse lines, overseeing large datasets, and providing training for lab personnel. 

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PhD Candidate 2027

Courtney Manning

Ms. Manning is a graduate student who is curious about counter regulatory mechanisms in response to insulin induced hypoglycemia. She is interested in discovering better mechanisms to counteract insulin over doses in people with T1DM.

Technical Team

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Krissy Campbell

Lab Administrator

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Alex Chen

Technician 

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Don Wothe

Technician

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Marshall Paisley

Technician

© 2024 by D Leander

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