Publications since 2015. DMPI-Endo members in Bold.
2025
Ectopic, hepatic GLP-1R agonism enhances the weight loss efficacy of GLP-1 analogues​​
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Jonathan D Douros, Megan Capozzi, Aaron Novikoff, Jacek Mokrosinski, Barent DuBois, Joseph Stock, Rebecca Rohlfs, Mikayla Anderson, Dominika J Jedrzejcyk, Svend Poulsen, Erik Oude Blenke, Tomas Dago, Kasper Huus, Sune Kobberup, Marita Rivir, Joyce Sorrell, Stephanie Mowery, Daniel J Drucker, David A D'Alessio, Jonathan E Campbell, Timo D Muller, Diego Perez-Tilve, Patrick J Knerr, Brian Finan
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bioRxiv
Glucose-dependent insulinotropic polypeptide (GIP)
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Timo D Müller, Alice Adriaenssens, Bo Ahrén, Matthias Blüher, Andreas Birkenfeld, Jonathan E Campbell, Matthew P Coghlan, David D’Alessio, Carolyn F Deacon, Stefano DelPrato, Jonathan D Douros, Daniel J Drucker, Natalie S Figueredo Burgos, Peter R Flatt, Brian Finan, Ruth E Gimeno, Fiona M Gribble, Matthew R Hayes, Christian Hölscher, Jens J Holst, Patrick J Knerr, Filip K Knop, Christine M Kusminski, Arkadiusz Liskiewicz, Guillaume Mabilleau, Stephanie A Mowery, Michael A Nauck, Aaron Novikoff, Frank Reimann, Anna G Roberts, Mette M Rosenkilde, Ricardo J Samms, Philip E Scherer, Randy J Seeley, Kyle W Sloop, Christian Wolfrum, Denise Wootten, Richard D DiMarchi, Matthias H Tschöp
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Molecular Metabolism
Islet hormones at the intersection of glucose and amino acid metabolism
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Phillip J White, Nicolai J Wewer Albrechtsen, Jonathan E Campbell
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Nature Reviews Endocrinology
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Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Hamdah Al-Nebaihi, Amanda A Greenwell, Melinda Wuest, Jenilee Woodfield, Rabih Abou Farraj, Christina T Saed, Jordan SF Chan, Rakesh K Bhat, Indiresh A Mangra-Bala, Tanin Shafaati, Keshav Gopal, Farah Eaton, Sally R Ferrari, Cory S Wagg, Megan E Capozzi, Jonathan E Campbell, Michael Overduin, Carlos A Velazquez-Martinez, JN Mark Glover, Frank Wuest, Dion R Brocks, John R Ussher
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iScience
2024
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Antwi-Boasiako Oteng, Liu Liu, Yinghong Cui, Oksana Gavrilova, Huiyan Lu, Min Chen, Lee S Weinstein, Jonathan E Campbell, Jo E Lewis, Fiona M Gribble, Frank Reimann, Juergen Wess
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Journal of Clinical Investigation
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Antwi-Boasiako Oteng, Liu Liu, Yinghong Cui, Oksana Gavrilova, Huiyan Lu, Min Chen, Lee S Weinstein, Jonathan E Campbell, Jo E Lewis, Fiona M Gribble, Frank Reimann, Jürgen Wess
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The Journal of Clinical Investigation
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Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob S Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Lærke S Gasbjerg, Jacek MokrosiÅ„ski, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D’Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik T Sørensen, Allan Vaag, Jens S Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens J Holst, Torben Hansen, Shane C Wright, Volker M Lauschke, Niels Grarup, Alexander S Hauser, Mette M Rosenkilde
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Nature Metabolism
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Sophie L Lewandowski, Kimberley El, and Jonathan E Campbell
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American Journal of Physiology-Endocrinology and Metabolism
Intra-islet Alpha-cell Gs signaling promotes glucagon release
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Liu Liu, Kimberley El, Diptadip, Luiz F Barella, Yinghong Cui, Sarah M Gray, Carla Guedikian, Min Chen, Lee S Weinstein, Emily Knuth, Matthew J Merrins, Jeffery Roman, Klaus H Kaestner, Nicolai Doliba, Jonathan E Campbell, and Jurgen Wess
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Nature Communications
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Sarah M Gray, Elisha Goonatilleke, Michelle A Emrick, Jessica O Becker, Andrew N Hoofnagle, Darko Stefanovski, Wentao He, Guofang Zhang, Jenny Tong, Jonathan E Campbell, David D'Alessio
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American Diabetes Association
GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells, and delta cells
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Ali H Shilled, Katrina Viloria, Johannes Broichhagen, Jonathan E Campbell, David J Hodson
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Peptides
2023
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
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Kimberley El, Jonathan D Douros, Francis S Willard, Aaron Novikoff, Ashot Sargsyan, Diego Perez-Tilve, David B Wainscott, Bin Yang, Alex Chen, Donald Wothe, Callum Coupland, Mattias H Tschöp, Brian Finan, David A D'Alessio, Kyle W Sloop, Timo D Muller, Jonathan E Campbell
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Nature Metabolism
Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
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Evgenia Fadzeyeva, Cassandra A A Locatelli, Natasha A Trzaskalski, My-Anh Nguyen, Megan E Capozzi, Branka Vulesevic, Nadya M Morrow, Peyman Ghorbani, Antonio A Hanson, Ilka Lorenzen-Schmidt, Mary-Anne Doyle, Richard Seymour, Elodie M Varin, Morgan D Fullerton, Jonathan E Campbell, Erin E Mulvihill
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JCI Insight
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Alice Adriaenssens, Johannes Broichhagen, Anne de Bray, Julia Ast, Annie Hasib, Ben Jones, Alejandra Tomas, Natalie Figueredo Burgos, Orla Woodward, Jo Lewis, Elisabeth O'Flaherty, Kimberley El, Canqi Cui, Norio Harada, Nobuya Inagaki, Jonathan Campbell, Daniel Brierley, David J Hodson, Ricardo Samms, Fiona Gribble, Frank Reimann
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JCI Insight
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Thao D V Le, Payam Fathi, Amanda B Watters, Blair J Ellis, Gai-Linn K Besing, Nadejda Bozadjieva-Kramer, Misty B Perez, Andrew I Sullivan, Jesse P Rose, Laurie L Baggio , Jacqueline Koehler, Jennifer L Brown, Michelle B Bales, Kaitlyn G Nwaba, Jonathan Campbell, Daniel J Drucker, Matthew J Potthoff, Randy J Seeley, Julio E Ayala
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Molecular Metabolism
The ubiquitination status of the glucagon receptor determines signal bias
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Suneet Kaur, Badr Sokrat, Megan E Capozzi, Kimberley El, Yushi Bai, Aeva Jazic, Bridgette Han, Kaavya Krishna Kumar, David A. D'Alessio, Jonathan E Campbell, Michel Bouvier, Sudha K Shenoy
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Journal of Biological Chemistry
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Jack T Womble, Mark D Ihrie, Victoria L McQuade, Akhil Hegde, Matthew S McCravy, Sanat Phatak, Robert M Tighe, Loretta G Que, David A D'Alessio, Julia K L Walker, Jennifer L Ingram
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Frontiers in Endocrinology
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Imran Ozer, Anna Slezak, Parul Sirohi, Xinghai Li, Nikita Zakharov, Yunxin Yao, Jeffrey I Everitt, Ivan Spasojevic, Stephen L Craig, Joel H Collier, Jonathan E Campbell, David A. D'Alessio, Ashutosh Chilkoti
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Biomaterials
2022
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems
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Bin Yang, Vasily M Gelfanov, Kimberley El, Alex Chen, Rebecca Rohlfs, Barent DuBois, Ann Maria Kruse Hansen, Diego Perez-Tilve, Patrick J Knerr, David D'Alessio, Jonathan E Campbell, Jonathan D Douros, Brian Finan
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Molecular Metabolism
The past, present, and future physiology and pharmacology of glucagon
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Megan E Capozzi, David A D'Alessio, Jonathan E Campbell
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Cell Metabolism
GLP-1 mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice
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Carmelo Quarta, Kerstin Stemmer, Aaron Novikoff, Bin Yang, Felix Klingelhuber, Alex Harger, Mostafa Bakhti, Aimee Bastidas-Ponce, Eric Baugé, Jonathan E Campbell, Megan Capozzi, Christoffer Clemmensen, Gustav Collden, Perla Cota, Jon Douros, Daniel J Drucker, Barent DuBois, Annette Feuchtinger, Cristina Garcia-Caceres, Gerald Grandl, Nathalie Hennuyer, Stephan Herzig, Susanna M Hofmann, Patrick J Knerr, Konxhe Kulaj, Fanny Lalloyer, Heiko Lickert, Arek Liskiewicz, Daniela Liskiewicz, Gandhari Maity, Diego Perez-Tilve, Sneha Prakash, Miguel A Sanchez-Garrido, Qian Zhang, Bart Staels, Natalie Krahmer, Richard D DiMarchi, Matthias H Tschöp, Brian Finan, Timo D Müller
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Nature Metabolism
Ildr1 gene deletion protects against diet-induced obesity and hyperglycemia
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Rashmi Chandra, Dipendra K Aryal, Jonathan D Douros, Rafiq Shahid, Supriya J Davis, Jonathan E Campbell, Olga Ilkayeya, Phillip J White, Ramona Rodriguez, Christopher B Newgard, William C Wetsel, Rodger A Liddle
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Plos One
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Shweta Urva, Tamer Coskun, Mei Teng Loh, Yu Du, Melissa K Thomas, Sirel Gurbuz, Axel Haupt, Charles T Benson, Martha Hernandez-Illas, David A D'Alessio, Zvonko Milicevic
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Lancet
Risk factors for the development or progression of diabetic retinopathy in pregnancy: Meta-analysis and systematic review
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Swara M Sarvepalli, Beth A Bailey, David A D'Alessio, Madleen Lemaitre, Anne Vambergue, Jay Rathinavelu, Majda Hadziahmetovic
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Clinical and Experimental Ophthalmology
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Michael A Nauck, David A D'Alessio
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Cardiovascular Diabetology
The GIPR is predominantly localized to non-adipocyte cell types within white adipose tissue.
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Jonathan E. Campbell, Jacquline L. Beaudry, Berit Svendsen, Laurie L. Baggio, Andrew N. Gordon, John R. Ussher, Chi Kin Wong, Fiona M. Gribble, David A. D'Alessio, Frank Reimann, Daniel J. Drucker.
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Diabetes
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Sarah C Nyirjesy, Amy J Peleckis, Jack N Eiel, Kathryn Gallagher, Andriana Doliba, Abigail Tami, Anneliese J Flatt, Diva D De Leon, Denis Hadjiliadis, Saba Sheikh, Darko Stefanovski, Robert Gallop, David A D'Alessio, Ronald C Rubenstein, Andrea Kelly, Michael R Rickels
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Cardiovascular Diabetology
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Darren K McGuire, David A D'Alessio, Stephen J Nicholls, Steven E Nissen, Jeffrey S Riesmeyer, Imre Pavo, Shanthi Sethuraman, Cory R Heilmann, John J Kaiser, Govinda J Weerakkody
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Cardiovascular Diabetology
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Sarah M Gray, Andrew L Hoselton, Radha Krishna, Cris A Slentz, David A D'Alessio
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Journal of Clinical Endocrinology and Metabolism
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Nitya Kumar, David A D'Alessio
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Journal of Clinical Endocrinology and Metabolism
A Lesson from 2020: Public Health Matters for Both COVID-19 and Diabetes
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Matthew C Riddle, George Bakris, Lawrence Blonde, Andrew JM Boulton, David A D'Alessio, Linda A DiMeglio, Linda Gonder-Frerick, Korey K Hood, Frank B Hu, Steven E Kahn, Sanjay Paul, Lawrence A Leiter, Robert G Moses, Stephen S Rich, Julio Rosenstock, Judith Wylie-Rosett
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Diabetes Care
2021
GIP mediates the incretin effect and glucose tolerance by dual actions on alpha cells and beta cells
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Kimberley El, Sarah M. Gray, Megan E. Capozzi, Emily R. Knuth, Erli Jin, Berit Svendsen, Alexis Clifford, Jennifer L. Brown, Bryanna M. Chazotte, Kyle W. Sloop, Derek J. Nunez, Matthew J. Merrins, David A. D'Alessio, Jonathan E. Campbell
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Science Advances
Extreme elevations of low-density lipoprotein cholesterol with very low carbohydrate, high fat diets
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Schaffer AE, D'Alessio DA, Guyton JR.
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J Clin Lipidol
Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes
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Alonge KM, D'Alessio DA, Schwartz MW
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Diabetologia
Mechanisms controlling pancreatic islet cell function in insulin secretion
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Jonathan E. Campbell, Christopher B. Newgard
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Nature Reviews Molecular Cell Biology
2020
Revisiting the complexity of GLP-1 action - from sites of synthesis to receptor activation
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Brent A. McLean, Chi Kin Wong, Jonathan E. Campbell, David J. Hodson, Stefan Trapp, Daniel J. Drucker
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Endocrine Reviews
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion
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Guo-Fang Zhang, Mette V. Jensen, Sarah M. Gray, Kimberley El, You Wang, Danhong Lu, Thomas C. Becker, Jonathan E. Campbell, Christopher B. Newgard
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Cell Metabolism
Targeting the GIPR for obesity: To agonize or antagonize? Potential mechanisms
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Jonathan E. Campbell
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Molecular Metabolism
Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway
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Sophie L. Lewandowski, Rebecca L. Cardone, Hannah R. Foster, Thuong Ho, Evgeniy Potapenko, Chetan Poudel, Halena R. VanDeusen, Sophia M. Sdao, Tiago C. Alves, Xiaojian Zhao, Megan E. Capozzi, Arnaldo H. de Souza, Ishrat Jahan, Craig J. Thomas, Craig S. Nunemaker, Dawn B. Davis, Jonathan E. Campbell, Richard G. Kibbey, Matthew J. Merrins
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Cell Metabolism
Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes
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Kimberly M. Alonge, David A D'Alessio, Michael W. Schwartz
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Diabetologia
Repositioning the alpha cell in postprandial metabolism
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Kimberley El, Megan E. Capozzi, Jonathan E. Campbell
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Endocrinology
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Frank K. Huynh, Brett S. Peterson, Kristin A. Anderson, Zhihong Lin, Aeowynn J. Coakley, Fiara M.S. Llaguno, Thi-Tina N. Nguyen, Jonathan E. Campbell, Samuel B. Stephens, Christopher B. Newgard, Matthew D. Hirschey
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American Journal of Physiology: Endocrinology and Metabolism
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Caslin A. Gilroy, Megan E. Capozzi, Anastasia K. Varanko, Jenny Tong, David A. D'Alessio, Jonathan E. Campbell, Ashutosh Chilkoti
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Science Advances
Could micro changes in beta-cells enable major changes in metabolism?
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Megan E. Capozzi, Jonathan E. Campbell
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EBioMedicine
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
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Francis S. Willard, Jonathan D. Douros, Maria B.N. Gabe, Aaron D. Showalter, David B. Wainscott, Todd M. Suter, Megan E. Capozzi, Wijnand J.C. van der Velden, Cynthia Stutsman, Guemalli R. Cardona, Shweta Urva, Paul J. Emmerson, Jens J. Holst, David A. D'Alessio, Matthew P. Coghlan, Mette M. Rosenkilde, Jonathan E. Campbell, Kyle W. Sloop
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JCI Insight
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Ranee Chatterjee, Clementine A. Davenport, Lydia Kwee, David D'Alessio, Laura P. Svetkey, Pao-Hwa Lin, Cris A. Slentz, Olga Ilkayeva, Johanna Johnson, David Edelman, Svati H Shah
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Metabolomics
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Bonnie Brehm, Suzanne Summer, Todd Jenkins, David D'Alessio, Thomas Inge
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Surgery for Obesity and Related Disorders
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Jeremy H. Pettus, David A D'Alessio, Juan P. Frias, Eric G. Vajda, James D. Pipkin, Julio Rosenstock, Gretchen Williamson, Miriam A. Zangmeister, Lin Zhi, Keith B. Marschke
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Diabetes Care
Discordance between GLP-1R gene and protein expression in mouse pancreatic islets cells
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Sarah M. Gray, Yurong Xin, Elizabeth C. Ross, Bryanna M. Chazotte, Megan E. Capozzi, Kimberley El, Berit Svendsen, Peter Ravn, Kyle W. Sloop, Jenny Tong, Jesper Gromada, Jonathan E. Campbell, David A. D'Alessio
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Journal of Biological Chemistry
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Rami Al Batran, Keshav Goal, Megan E. Capozzi, Jadin J. Chahade, Bruno Saleme, S. Amirhossein Tabatabaei-Dakhili, Amada A. Greenwell, Jingjing Nui, Malak Almutairi, Nikole J. Myme, Grant Masson, Ryekjang Kim, Carlos A. Velazquez-Martinez, Celine Agues, Peter A. Crawford, Gopinath Sutendra, Jonathan E. Campbell, Jason R.B. Dyck, John R. Ussher.
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Cell Metabolism
The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition
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Megan E. Capozzi, Reilly W. Coch, Jepchumba Koech, Inna I. Astapova, Jacob B. Wait, Sara E. Encisco, Jonathan D. Douros, Kimberly El, Brian Finan, Kyle W. Sloop, Mark A. Herman, David A. D’Alessio, Jonathan E. Campbell
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Diabetes
2019
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John B Buse, Deborah J Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A D'Alessio, Melanie J Davies
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Diabetes Care
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John B Buse, Deborah J Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A D'Alessio, Melanie J Davies
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Diabetologia
Pharmacological Antagonism of the Incretin System Protects Against Diet-induced Obesity.
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Berit Svendsen, Megan E Capozzi, Jingjing Nui, Sarah A Hannou, Brian Finan, Jacqueline Naylor, Peter Ravn, David A D’Alessio, Jonathan E Campbell.
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Molecular Metabolism
Rapid hepatic metabolism blunts the endocrine actions of portally infused GLP-1 in male rats.
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Benedikt A Aulinger, Marta Perabo, Randy J Seeley, Klaus G Parhofer, David A D'Alessio
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American Journal of Physiology Endocrinology and Metabolism
The effects of preioperative dexamethasone on glycemic control and postoperative outcomes.
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Rebecca A Herbst, Onala T Telford, John Hunting, W Michael Bullock, Erin Manning, Beatrics D Hong, David A D'Alessio, Tracy L Setji
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Endocrine Practice
L-citrulline supplementation improvew glucose and exercise tolerance in obese male mice
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Amina Eshreif, Rami Al Batran, K Lockhart Jamieson, Ahmed M Darwesh, Keshav Gopal, Amanda A Greenwell, Igor Zlobine, Hanin Aburasayn, Farah Eaton, Erin E Mulvihill, Jonathan E Campbell, John M Seubert, John R Ussher
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Experimental Physiology
The role of GIP in α-cells and glucagon secretion
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Kimberley El, Jonathan E Campbell
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Peptides
Physiological roles of the GIP receptor in murine brown adipose tissue
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Jacqueline L Beaudry, Kiran D Kaur, Elodie M Varin, Laurie L Baggio, Xiemin Cao, Erin E Mulvihill, Holly E Bates, Jonathan E Campbell, Daniel J Drucker
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Molecular Metabolism
The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control
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Jonathan D Douros, Jenny Tony, David A D'Alessio
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Endocrine Reviews
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Jonathan D Douros, Jingjing Niu, Sophia Sdao, Trillian Gregg, Matthew J Merrins, Jonathan Campbell, Jenny Tong, David D'Alessio
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Molecular Metabolism
The role of GIP and pancreatic GLP-1 in the glucoregulatory effect of DPP-4 inhibition in mice.
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Chelsea R. Hutch, Karen Roelofs, April Haller, Joyce Sorrell, Kyle Leix, David A. D'Alessio, Robert Augustin, Randy J. Seeley, Thomas Klein, Darleen A. Sandoval
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Diabetologia
Beta-cell sensitivity to insulinotropic gut hormones is reduced after gastric bypass surgery
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Marzieh Salehi, Amalia Gastaldelli, David A D'Alessio
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Gut
One small step for mice, one giant leap for GWAS?
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Mark A Herman, Jonathan E Campbell, David A D’Alessio
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Journal of Clinical Investigation
Glucagon lowers glycemia when β cells are active
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Megan E Capozzi, Jacob B Wait, Andrew N Gordon Jepchumba Koech, Reilly W Coch, Berit Svendsen, Brian Finan, David A D’Alessio, Jonathan E Campbell
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JCI Insight
Intra-Islet Ghrelin Signaling does not Regulate Insulin Secretion from Adult Mice
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Sarah M Gray, Jingjing Niu, Amanda Zhang, Berit Svendsen, Jonathan E Campbell, David A D’Alessio, Jenny Tong
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Diabetes
Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes
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Brian Finan, Megan E Capozzi, Jonathan E Campbell
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Diabetes
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Marzieh Salehi, Amalia Gastaldelli, David A D'Alessio
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Diabetes, Obesity, and Metabolism
Reg3 Proteins as Gut Hormones? Don’t Be Hasty
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Jonathan D Douros, Jonathan E Campbell
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Endocrinology
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Jacqueline L Beaudry, Kiran Deep Kaur, Elodie M Varin, Laurie L Baggio, Xiemin Cao, Erin E Mulvihill, Jennifer H Stern, Jonathan E Campbell, Phillip E Scherer, Daniel J Drucker
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Molecular Metabolism
Sleeve gastrectomy rapidly enhances islet function independently of body weight
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Jonathan D Douros, Jingjing Niu, Sophia Sdao, Trillian Gregg, Kelsey Fisher-Wellman, Manish Bharadwaj, Anthony Molina, Ramamani Arumugam, MacKenzie Martin, Enrico Petretto, Matthew J Merrins, Mark A Herman, Jenny Tong, Jonathan E Campbell, David A D’Alessio
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JCI Insight
Beta Cell tone is defined by proglucagon peptides through cAMP signaling
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Megan E Capozzi, Berit Svendsen, Sara E Encisco, Sophie L Lewandowski, Mackenzie D Martin, Haopeng Lin, Justin L Jaffe, Reilly W Coch, Jonathan M Haldeman, Patrick E MacDonald, Matthew J Merrins, David A D’Alessio, Jonathan E Campbell
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JCI Insight
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Elodie M Varin, Erin E Mulvihill, Jacqueline L Beaudry, Gemma Pujadas, Shai Fuchs, Jean-François Tanti, Sofia Fazio, Kirandeep Kaur, Xiemin Cao, Laurie L Baggio, Dianne Matthews, Jonathan E Campbell, Daniel J Drucker
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Cell Metabolism
2018
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Melanie J Davies, David A D'Alessio, Judith Fradkin, Walter N Kernan, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Apostolos Tsapas, Deborah J Wexler, John B Buse
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Diabetologia
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Melanie J Davies, David A D'Alessio, Judith Fradkin, Walter N Kernan, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Apostolos Tsapas, Deborah J Wexler, John B Buse
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Diabetes
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Rami Al Batran, Keshav Gopal, Mackenzie D Martin, Kim L Ho, Malak Almutairi, Hanin Aburasayn, Farah Eaton, Jonathan E Campbell, John R Ussher
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Diabetologia
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Tamer Coskun, Kyle W Sloop, Corina Loghin, Jorge Alsina-Fernandex, Shweta Urva, Krister B Bokvist, Xuewei Cui, Daniel A Briere, Over Cabrera, William C Roell, Uma Juchibholta, Julie S Moyers, Charles T Benson, Ruth E Gimeno, David A D'Alessio, Axel Haupt
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Molecular Metabolism
Interaction of GLP-1 and Ghrelin on Glucose Tolerance in Healthy Humans
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Laura C Page, Amalia Gastaldelli, Sarah M Gray, David A D'Alessio, Jenny Tong
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Diabetes
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Jonathan D Douros, Alfor G Lewis, Eric P Smith, JingJing Niu, Megan Capozzi, April Wittmann, Jonathan Campbell, Jenny Tong, Constance Wagner, Parinaz Mahbod, Randy Seeley, David A D’Alessio
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Diabetes
Can we RISE to the Challenge of Youth-Onset Type 2 Diabetes?
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John B Buse, David A D'Alessio, Matthew C Riddell
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Diabetes Care
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Brett S Peterson, Jonathan E Campbell, Olga Ilkayeva, Paul A Grimsrud, Matthew D Hirschey, Christopher B Newgard
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Cell Reports
Targeting the incretin/glucagon system with triagonists to treat diabetes
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Megan E Capozzi, Richard D DiMarchi, Matthias H Tschöp, Brian Finan, Jonathan E Campbell
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Endocrine Reviews
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John R Ussher, Jonathan E Campbell, Erin E Mulvihill, Laurie L Baggio, Holly E Bates, Brent A McLean, Keshav Gopal, Megan Capozzi, Bernardo Yusta, Xiemin Cao, Safina Ali, Minsuk Kim, M Golam Kabir, Yutaka Seino, Jinya Suzuki, Daniel J Drucker
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Cell Metabolism
2017
Metformin Use May Moderate the Effect of DPP-4 Inhibitors on Cardiovascular Outcomes
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Matthew J Crowley, John W Williams, Andrzej S Kosinski, David A D'Alessio, John B Buse
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Diabetes Care
β-cell inactivation of GPR119 unmasks incretin dependence of GPR119-mediated glucoregulation
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Brandon L Panaro, Grace B Flock, Jonathan E Campbell, Jacqueline L Beaudry, Xiemin Cao, Daniel J Drucker
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Diabetes
SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion
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Kristin A Anderson, Frank K Huynh, Kelsey Fisher-Wellman, J Darren Stuart, Brett S Peterson, Jonathan D Douros, Gregory R Wagner, J Will Thompson, Andreas S Madsen, Michelle F Green, R Michael Sivley, Olga R Ilkayeva, Robert D Stevens, Donald S Backos, John A Capra, Christian A Olsen, Jonathan E Campbell, Deborah M Muoio, Paul A Grimsrud, Matthew D Hirschey
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Cell Metabolism
DREADDing proglucagon neurons: a fresh look at metabolic regulation by the brain
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Jonathan E Campbell, David A D’Alessio
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Journal of Clinical Investigation
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Sriparna Ghosal, Amy EB Packard, Parinaz Mahbod, Jessica M McKlveen, Randy J Seeley, Brent Myers, Yvonne Ulrich-Lai, Eric P Smith, David A D'Alessio, James P Herman
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Journal of Neuroscience
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Erin E Mulvihill, Elodie M Varin, Bojana Gladanac, Jonathan E Campbell, John R Ussher, Laurie L Baggio, Bernardo Yusta, Jennifer Ayala, Melissa A Burmeister, Dianne Matthews, KW Annie Bang, Julio E Ayala, Daniel J Drucker
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Cell Metabolism
2016
Incretin-based therapies for the failing heart
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John R Ussher, Jonathan E Campbell
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Cardiovascular Endocrinology & Metabolism
Mechanisms of surgical control of type 2 diabetes: GLP-1 is the key factor - Maybe
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Marzieh Salehi, David A D'Alessio
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Surgery for Obesity and Related Disease
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Erin E Mulvihill, Elodie M Varin, John R Ussher, Jonathan E Campbell, KW Annie Bang, Tahmid Abdullah, Laurie L Baggio, Daniel J Drucker
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Diabetes
Bariatric/metabolic surgery for diabetes: Incorporating a powerful treatment into standard care
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Bruce M Wolfe, David A D'Alessio
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Obesity
TCF1 links GIPR signaling to the control of beta cell function and survival
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Jonathan E Campbell, John R Ussher, Erin E Mulvihill, Jelena Kolic, Laurie L Baggio, Xiemen Cao, Yu Liu, Benjamin J Lamont, Tsukasa Morii, Catherine J Streutker, Natalia Tamarina, Louis H Philipson, Jeffrey L Wrana, Patrick E MacDonald, Daniel J Drucker
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Nature Medicine
The incretin effect in obese adolescents with and without type 2 diabetes: impaired or intact?
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Benedikt A Aulinger, Torsten P Vahl, Ron L Prigeon, David A D'Alessio, Deborah A Elder
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American Journal of Physiology Endocrinology and Metabolism
2015
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Roger D Gibb, Johnson W McRorie, Darrel A Russell, Vic Hasselblad, David A D'Alessio
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Amercial Journal of Clincial Nutrition
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Thomas H Inge, Ronald L Prigeon, Deborah A Elder, Todd M Jenkins, Robert M Cohen, Stavra A Xanthakos, Stephen C Benoit, Lawrence M Dolan, Stephen R Daniels, David A D'Alessio
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Journal of Pediatrics
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Daniel Oropeza, Nathalie Jouvet, Lionel Budry, Jonathan E Campbell, Khalil Bouyakdan, Julie Lacombe, Gabrielle Perron, Valerie Bergeron, Joshua C Neuman, Harpreet K Brar, Rachel J Fenske, Clemence Meunier, Sarah Sczelecki, Michelle E Kimple, Daniel J Drucker, Robert A Screaton, Vincent Poitout, Mathieu Ferron, Thierry Alquier, Jennifer L Estall
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Diabetes
Islet α cells and glucagon—critical regulators of energy homeostasis
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Jonathan E Campbell, Daniel J Drucker
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Nature Reviews Endocrinology
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Denovan P Begg, Aaron A May, Joram D Mul, Min Liu, David A D'Alessio, Randy J Seeley, Stephen C Woods
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Diabetes
Glucagon-like peptide-1 receptor agonists increase pancreatic mass by induction of protein synthesis
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Jacqueline A Koehler, Laurie L Baggio, Xiemin Cao, Tahmid Abdulla, Jonathan E Campbell, Thomas Secher, Jacob Jelsing, Brett Larsen, Daniel J Drucker
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Diabetes
Diet-induced obese mice retain endogenous leptin action
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Nickki Ottaway, Parinaz Mahbod, Belen Rivero, Lee Ann Norman, Arieh Gertler, David A D'Alessio, Diego Perez-Tilve
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Cell Metabolism
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
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Brian Finan, Bin Yang, Nickki Ottaway, David L Smiley, Tao Ma, Christoffer Clemmensen, Joe Chabenne, Lianshan Zhang, Kirk M Habegger, Katrin Fischer, Jonathan E Campbell, Darleen Sandoval, Randy J Seeley, Konrad Bleicher, Sabine Uhles, William Riboulet, Jürgen Funk, Cornelia Hertel, Sara Belli, Elena Sebokova, Karin Conde-Knape, Anish Konkar, Daniel J Drucker, Vasily Gelfanov, Paul T Pfluger, Timo D Müller, Diego Perez-Tilve, Richard D DiMarchi, Matthias H Tschöp
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Nature Medicine
This information is intended to be a resource for members of the DMPI Endocrinology group