Publications since 2015. DMPI-Endo members in Bold.
2025
Ectopic, hepatic GLP-1R agonism enhances the weight loss efficacy of GLP-1 analogues
Jonathan D Douros, Megan Capozzi, Aaron Novikoff, Jacek Mokrosinski, Barent DuBois, Joseph Stock, Rebecca Rohlfs, Mikayla Anderson, Dominika J Jedrzejcyk, Svend Poulsen, Erik Oude Blenke, Tomas Dago, Kasper Huus, Sune Kobberup, Marita Rivir, Joyce Sorrell, Stephanie Mowery, Daniel J Drucker, David A D'Alessio, Jonathan E Campbell, Timo D Muller, Diego Perez-Tilve, Patrick J Knerr, Brian Finan
bioRxiv
Glucose-dependent insulinotropic polypeptide (GIP)
Timo D Müller, Alice Adriaenssens, Bo Ahrén, Matthias Blüher, Andreas Birkenfeld, Jonathan E Campbell, Matthew P Coghlan, David D’Alessio, Carolyn F Deacon, Stefano DelPrato, Jonathan D Douros, Daniel J Drucker, Natalie S Figueredo Burgos, Peter R Flatt, Brian Finan, Ruth E Gimeno, Fiona M Gribble, Matthew R Hayes, Christian Hölscher, Jens J Holst, Patrick J Knerr, Filip K Knop, Christine M Kusminski, Arkadiusz Liskiewicz, Guillaume Mabilleau, Stephanie A Mowery, Michael A Nauck, Aaron Novikoff, Frank Reimann, Anna G Roberts, Mette M Rosenkilde, Ricardo J Samms, Philip E Scherer, Randy J Seeley, Kyle W Sloop, Christian Wolfrum, Denise Wootten, Richard D DiMarchi, Matthias H Tschöp
Molecular Metabolism
Islet hormones at the intersection of glucose and amino acid metabolism
Phillip J White, Nicolai J Wewer Albrechtsen, Jonathan E Campbell
Nature Reviews Endocrinology
Development of a succinyl CoA: 3-ketoacid CoA transferase inhibitor with preference for peripheral versus central tissues that improves glycemia
Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Hamdah Al-Nebaihi, Amanda A Greenwell, Melinda Wuest, Jenilee Woodfield, Rabih Abou Farraj, Christina T Saed, Jordan SF Chan, Rakesh K Bhat, Indiresh A Mangra-Bala, Tanin Shafaati, Keshav Gopal, Farah Eaton, Sally R Ferrari, Cory S Wagg, Megan E Capozzi, Jonathan E Campbell, Michael Overduin, Carlos A Velazquez-Martinez, JN Mark Glover, Frank Wuest, Dion R Brocks, John R Ussher
iScience
2024
Activation of Gs K cells greatly improves obesity-and diabetes-related metabolic deficits signaling in mouse enteroendocrine
Antwi-Boasiako Oteng, Liu Liu, Yinghong Cui, Oksana Gavrilova, Huiyan Lu, Min Chen, Lee S Weinstein, Jonathan E Campbell, Jo E Lewis, Fiona M Gribble, Frank Reimann, Juergen Wess
Journal of Clinical Investigation
Activation of Gs signaling in mouse enteroendocrine K cells greatly improves obesity- and diabetes-related metabolic deficits
Antwi-Boasiako Oteng, Liu Liu, Yinghong Cui, Oksana Gavrilova, Huiyan Lu, Min Chen, Lee S Weinstein, Jonathan E Campbell, Jo E Lewis, Fiona M Gribble, Frank Reimann, Jürgen Wess
The Journal of Clinical Investigation
Characterization of genetic variants of GIPR reveals a contribution of B-arrestin to metabolic phenotypes
Hüsün S Kizilkaya, Kimmie V Sørensen, Jakob S Madsen, Peter Lindquist, Jonathan D Douros, Jette Bork-Jensen, Alessandro Berghella, Peter A Gerlach, Lærke S Gasbjerg, Jacek Mokrosiński, Stephanie A Mowery, Patrick J Knerr, Brian Finan, Jonathan E Campbell, David A D’Alessio, Diego Perez-Tilve, Felix Faas, Signe Mathiasen, Jørgen Rungby, Henrik T Sørensen, Allan Vaag, Jens S Nielsen, Jens-Christian Holm, Jeannet Lauenborg, Peter Damm, Oluf Pedersen, Allan Linneberg, Bolette Hartmann, Jens J Holst, Torben Hansen, Shane C Wright, Volker M Lauschke, Niels Grarup, Alexander S Hauser, Mette M Rosenkilde
Nature Metabolism
Evaluating glucose-dependent insulinotropic polypeptide and glucagon as key regulators of insulin secretion in the pancreatic islet
Sophie L Lewandowski, Kimberley El, and Jonathan E Campbell
American Journal of Physiology-Endocrinology and Metabolism
Intra-islet Alpha-cell Gs signaling promotes glucagon release
Liu Liu, Kimberley El, Diptadip, Luiz F Barella, Yinghong Cui, Sarah M Gray, Carla Guedikian, Min Chen, Lee S Weinstein, Emily Knuth, Matthew J Merrins, Jeffery Roman, Klaus H Kaestner, Nicolai Doliba, Jonathan E Campbell, and Jurgen Wess
Nature Communications
High Doses of exogenous glucagon stimulate insulin secretion and reduce insulin clearance in healthy humans
Sarah M Gray, Elisha Goonatilleke, Michelle A Emrick, Jessica O Becker, Andrew N Hoofnagle, Darko Stefanovski, Wentao He, Guofang Zhang, Jenny Tong, Jonathan E Campbell, David D'Alessio
American Diabetes Association
GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells, and delta cells
Ali H Shilled, Katrina Viloria, Johannes Broichhagen, Jonathan E Campbell, David J Hodson
Peptides
2023
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
Kimberley El, Jonathan D Douros, Francis S Willard, Aaron Novikoff, Ashot Sargsyan, Diego Perez-Tilve, David B Wainscott, Bin Yang, Alex Chen, Donald Wothe, Callum Coupland, Mattias H Tschöp, Brian Finan, David A D'Alessio, Kyle W Sloop, Timo D Muller, Jonathan E Campbell
Nature Metabolism
Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
Evgenia Fadzeyeva, Cassandra A A Locatelli, Natasha A Trzaskalski, My-Anh Nguyen, Megan E Capozzi, Branka Vulesevic, Nadya M Morrow, Peyman Ghorbani, Antonio A Hanson, Ilka Lorenzen-Schmidt, Mary-Anne Doyle, Richard Seymour, Elodie M Varin, Morgan D Fullerton, Jonathan E Campbell, Erin E Mulvihill
JCI Insight
Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding
Alice Adriaenssens, Johannes Broichhagen, Anne de Bray, Julia Ast, Annie Hasib, Ben Jones, Alejandra Tomas, Natalie Figueredo Burgos, Orla Woodward, Jo Lewis, Elisabeth O'Flaherty, Kimberley El, Canqi Cui, Norio Harada, Nobuya Inagaki, Jonathan Campbell, Daniel Brierley, David J Hodson, Ricardo Samms, Fiona Gribble, Frank Reimann
JCI Insight
Fibroblast growth factor-21 is required for weight loss induced by the glucagon-like peptide-1 receptor agonist liraglutide in male mice fed high carbohydrate diets
Thao D V Le, Payam Fathi, Amanda B Watters, Blair J Ellis, Gai-Linn K Besing, Nadejda Bozadjieva-Kramer, Misty B Perez, Andrew I Sullivan, Jesse P Rose, Laurie L Baggio , Jacqueline Koehler, Jennifer L Brown, Michelle B Bales, Kaitlyn G Nwaba, Jonathan Campbell, Daniel J Drucker, Matthew J Potthoff, Randy J Seeley, Julio E Ayala
Molecular Metabolism
The ubiquitination status of the glucagon receptor determines signal bias
Suneet Kaur, Badr Sokrat, Megan E Capozzi, Kimberley El, Yushi Bai, Aeva Jazic, Bridgette Han, Kaavya Krishna Kumar, David A. D'Alessio, Jonathan E Campbell, Michel Bouvier, Sudha K Shenoy
Journal of Biological Chemistry
Vertical sleeve gastrectomy associates with airway hyperresponsiveness in a murine model of allergic airway disease and obesity
Jack T Womble, Mark D Ihrie, Victoria L McQuade, Akhil Hegde, Matthew S McCravy, Sanat Phatak, Robert M Tighe, Loretta G Que, David A D'Alessio, Julia K L Walker, Jennifer L Ingram
Frontiers in Endocrinology
Imran Ozer, Anna Slezak, Parul Sirohi, Xinghai Li, Nikita Zakharov, Yunxin Yao, Jeffrey I Everitt, Ivan Spasojevic, Stephen L Craig, Joel H Collier, Jonathan E Campbell, David A. D'Alessio, Ashutosh Chilkoti
Biomaterials
2022
Discovery of a potent GIPR peptide antagonist that is effective in rodent and human systems
Bin Yang, Vasily M Gelfanov, Kimberley El, Alex Chen, Rebecca Rohlfs, Barent DuBois, Ann Maria Kruse Hansen, Diego Perez-Tilve, Patrick J Knerr, David D'Alessio, Jonathan E Campbell, Jonathan D Douros, Brian Finan
Molecular Metabolism
The past, present, and future physiology and pharmacology of glucagon
Megan E Capozzi, David A D'Alessio, Jonathan E Campbell
Cell Metabolism
GLP-1 mediated delivery of tesaglitazar improves obesity and glucose metabolism in male mice
Carmelo Quarta, Kerstin Stemmer, Aaron Novikoff, Bin Yang, Felix Klingelhuber, Alex Harger, Mostafa Bakhti, Aimee Bastidas-Ponce, Eric Baugé, Jonathan E Campbell, Megan Capozzi, Christoffer Clemmensen, Gustav Collden, Perla Cota, Jon Douros, Daniel J Drucker, Barent DuBois, Annette Feuchtinger, Cristina Garcia-Caceres, Gerald Grandl, Nathalie Hennuyer, Stephan Herzig, Susanna M Hofmann, Patrick J Knerr, Konxhe Kulaj, Fanny Lalloyer, Heiko Lickert, Arek Liskiewicz, Daniela Liskiewicz, Gandhari Maity, Diego Perez-Tilve, Sneha Prakash, Miguel A Sanchez-Garrido, Qian Zhang, Bart Staels, Natalie Krahmer, Richard D DiMarchi, Matthias H Tschöp, Brian Finan, Timo D Müller
Nature Metabolism
Ildr1 gene deletion protects against diet-induced obesity and hyperglycemia
Rashmi Chandra, Dipendra K Aryal, Jonathan D Douros, Rafiq Shahid, Supriya J Davis, Jonathan E Campbell, Olga Ilkayeya, Phillip J White, Ramona Rodriguez, Christopher B Newgard, William C Wetsel, Rodger A Liddle
Plos One
Shweta Urva, Tamer Coskun, Mei Teng Loh, Yu Du, Melissa K Thomas, Sirel Gurbuz, Axel Haupt, Charles T Benson, Martha Hernandez-Illas, David A D'Alessio, Zvonko Milicevic
Lancet
Risk factors for the development or progression of diabetic retinopathy in pregnancy: Meta-analysis and systematic review
Swara M Sarvepalli, Beth A Bailey, David A D'Alessio, Madleen Lemaitre, Anne Vambergue, Jay Rathinavelu, Majda Hadziahmetovic
Clinical and Experimental Ophthalmology
Michael A Nauck, David A D'Alessio
Cardiovascular Diabetology
The GIPR is predominantly localized to non-adipocyte cell types within white adipose tissue.
Jonathan E. Campbell, Jacquline L. Beaudry, Berit Svendsen, Laurie L. Baggio, Andrew N. Gordon, John R. Ussher, Chi Kin Wong, Fiona M. Gribble, David A. D'Alessio, Frank Reimann, Daniel J. Drucker.
Diabetes
Sarah C Nyirjesy, Amy J Peleckis, Jack N Eiel, Kathryn Gallagher, Andriana Doliba, Abigail Tami, Anneliese J Flatt, Diva D De Leon, Denis Hadjiliadis, Saba Sheikh, Darko Stefanovski, Robert Gallop, David A D'Alessio, Ronald C Rubenstein, Andrea Kelly, Michael R Rickels
Cardiovascular Diabetology
Darren K McGuire, David A D'Alessio, Stephen J Nicholls, Steven E Nissen, Jeffrey S Riesmeyer, Imre Pavo, Shanthi Sethuraman, Cory R Heilmann, John J Kaiser, Govinda J Weerakkody
Cardiovascular Diabetology
Sarah M Gray, Andrew L Hoselton, Radha Krishna, Cris A Slentz, David A D'Alessio
Journal of Clinical Endocrinology and Metabolism
Nitya Kumar, David A D'Alessio
Journal of Clinical Endocrinology and Metabolism
A Lesson from 2020: Public Health Matters for Both COVID-19 and Diabetes
Matthew C Riddle, George Bakris, Lawrence Blonde, Andrew JM Boulton, David A D'Alessio, Linda A DiMeglio, Linda Gonder-Frerick, Korey K Hood, Frank B Hu, Steven E Kahn, Sanjay Paul, Lawrence A Leiter, Robert G Moses, Stephen S Rich, Julio Rosenstock, Judith Wylie-Rosett
Diabetes Care
2021
GIP mediates the incretin effect and glucose tolerance by dual actions on alpha cells and beta cells
Kimberley El, Sarah M. Gray, Megan E. Capozzi, Emily R. Knuth, Erli Jin, Berit Svendsen, Alexis Clifford, Jennifer L. Brown, Bryanna M. Chazotte, Kyle W. Sloop, Derek J. Nunez, Matthew J. Merrins, David A. D'Alessio, Jonathan E. Campbell
Science Advances
Extreme elevations of low-density lipoprotein cholesterol with very low carbohydrate, high fat diets
Schaffer AE, D'Alessio DA, Guyton JR.
J Clin Lipidol
Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes
Alonge KM, D'Alessio DA, Schwartz MW
Diabetologia
Mechanisms controlling pancreatic islet cell function in insulin secretion
Jonathan E. Campbell, Christopher B. Newgard
Nature Reviews Molecular Cell Biology
2020
Revisiting the complexity of GLP-1 action - from sites of synthesis to receptor activation
Brent A. McLean, Chi Kin Wong, Jonathan E. Campbell, David J. Hodson, Stefan Trapp, Daniel J. Drucker
Endocrine Reviews
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion
Guo-Fang Zhang, Mette V. Jensen, Sarah M. Gray, Kimberley El, You Wang, Danhong Lu, Thomas C. Becker, Jonathan E. Campbell, Christopher B. Newgard
Cell Metabolism
Targeting the GIPR for obesity: To agonize or antagonize? Potential mechanisms
Jonathan E. Campbell
Molecular Metabolism
Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway
Sophie L. Lewandowski, Rebecca L. Cardone, Hannah R. Foster, Thuong Ho, Evgeniy Potapenko, Chetan Poudel, Halena R. VanDeusen, Sophia M. Sdao, Tiago C. Alves, Xiaojian Zhao, Megan E. Capozzi, Arnaldo H. de Souza, Ishrat Jahan, Craig J. Thomas, Craig S. Nunemaker, Dawn B. Davis, Jonathan E. Campbell, Richard G. Kibbey, Matthew J. Merrins
Cell Metabolism
Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes
Kimberly M. Alonge, David A D'Alessio, Michael W. Schwartz
Diabetologia
Repositioning the alpha cell in postprandial metabolism
Kimberley El, Megan E. Capozzi, Jonathan E. Campbell
Endocrinology
Frank K. Huynh, Brett S. Peterson, Kristin A. Anderson, Zhihong Lin, Aeowynn J. Coakley, Fiara M.S. Llaguno, Thi-Tina N. Nguyen, Jonathan E. Campbell, Samuel B. Stephens, Christopher B. Newgard, Matthew D. Hirschey
American Journal of Physiology: Endocrinology and Metabolism
Caslin A. Gilroy, Megan E. Capozzi, Anastasia K. Varanko, Jenny Tong, David A. D'Alessio, Jonathan E. Campbell, Ashutosh Chilkoti
Science Advances
Could micro changes in beta-cells enable major changes in metabolism?
Megan E. Capozzi, Jonathan E. Campbell
EBioMedicine
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Francis S. Willard, Jonathan D. Douros, Maria B.N. Gabe, Aaron D. Showalter, David B. Wainscott, Todd M. Suter, Megan E. Capozzi, Wijnand J.C. van der Velden, Cynthia Stutsman, Guemalli R. Cardona, Shweta Urva, Paul J. Emmerson, Jens J. Holst, David A. D'Alessio, Matthew P. Coghlan, Mette M. Rosenkilde, Jonathan E. Campbell, Kyle W. Sloop
JCI Insight
Ranee Chatterjee, Clementine A. Davenport, Lydia Kwee, David D'Alessio, Laura P. Svetkey, Pao-Hwa Lin, Cris A. Slentz, Olga Ilkayeva, Johanna Johnson, David Edelman, Svati H Shah
Metabolomics
Bonnie Brehm, Suzanne Summer, Todd Jenkins, David D'Alessio, Thomas Inge
Surgery for Obesity and Related Disorders
Jeremy H. Pettus, David A D'Alessio, Juan P. Frias, Eric G. Vajda, James D. Pipkin, Julio Rosenstock, Gretchen Williamson, Miriam A. Zangmeister, Lin Zhi, Keith B. Marschke
Diabetes Care
Discordance between GLP-1R gene and protein expression in mouse pancreatic islets cells
Sarah M. Gray, Yurong Xin, Elizabeth C. Ross, Bryanna M. Chazotte, Megan E. Capozzi, Kimberley El, Berit Svendsen, Peter Ravn, Kyle W. Sloop, Jenny Tong, Jesper Gromada, Jonathan E. Campbell, David A. D'Alessio
Journal of Biological Chemistry
Rami Al Batran, Keshav Goal, Megan E. Capozzi, Jadin J. Chahade, Bruno Saleme, S. Amirhossein Tabatabaei-Dakhili, Amada A. Greenwell, Jingjing Nui, Malak Almutairi, Nikole J. Myme, Grant Masson, Ryekjang Kim, Carlos A. Velazquez-Martinez, Celine Agues, Peter A. Crawford, Gopinath Sutendra, Jonathan E. Campbell, Jason R.B. Dyck, John R. Ussher.
Cell Metabolism
The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition
Megan E. Capozzi, Reilly W. Coch, Jepchumba Koech, Inna I. Astapova, Jacob B. Wait, Sara E. Encisco, Jonathan D. Douros, Kimberly El, Brian Finan, Kyle W. Sloop, Mark A. Herman, David A. D’Alessio, Jonathan E. Campbell
Diabetes
2019
John B Buse, Deborah J Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A D'Alessio, Melanie J Davies
Diabetes Care
John B Buse, Deborah J Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A D'Alessio, Melanie J Davies
Diabetologia
Pharmacological Antagonism of the Incretin System Protects Against Diet-induced Obesity.
Berit Svendsen, Megan E Capozzi, Jingjing Nui, Sarah A Hannou, Brian Finan, Jacqueline Naylor, Peter Ravn, David A D’Alessio, Jonathan E Campbell.
Molecular Metabolism
Rapid hepatic metabolism blunts the endocrine actions of portally infused GLP-1 in male rats.
Benedikt A Aulinger, Marta Perabo, Randy J Seeley, Klaus G Parhofer, David A D'Alessio
American Journal of Physiology Endocrinology and Metabolism
The effects of preioperative dexamethasone on glycemic control and postoperative outcomes.
Rebecca A Herbst, Onala T Telford, John Hunting, W Michael Bullock, Erin Manning, Beatrics D Hong, David A D'Alessio, Tracy L Setji
Endocrine Practice
L-citrulline supplementation improvew glucose and exercise tolerance in obese male mice
Amina Eshreif, Rami Al Batran, K Lockhart Jamieson, Ahmed M Darwesh, Keshav Gopal, Amanda A Greenwell, Igor Zlobine, Hanin Aburasayn, Farah Eaton, Erin E Mulvihill, Jonathan E Campbell, John M Seubert, John R Ussher
Experimental Physiology
Physiological roles of the GIP receptor in murine brown adipose tissue
Jacqueline L Beaudry, Kiran D Kaur, Elodie M Varin, Laurie L Baggio, Xiemin Cao, Erin E Mulvihill, Holly E Bates, Jonathan E Campbell, Daniel J Drucker
Molecular Metabolism
The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control
Jonathan D Douros, Jenny Tony, David A D'Alessio
Endocrine Reviews
Jonathan D Douros, Jingjing Niu, Sophia Sdao, Trillian Gregg, Matthew J Merrins, Jonathan Campbell, Jenny Tong, David D'Alessio
Molecular Metabolism
The role of GIP and pancreatic GLP-1 in the glucoregulatory effect of DPP-4 inhibition in mice.
Chelsea R. Hutch, Karen Roelofs, April Haller, Joyce Sorrell, Kyle Leix, David A. D'Alessio, Robert Augustin, Randy J. Seeley, Thomas Klein, Darleen A. Sandoval
Diabetologia
Beta-cell sensitivity to insulinotropic gut hormones is reduced after gastric bypass surgery
Marzieh Salehi, Amalia Gastaldelli, David A D'Alessio
Gut
One small step for mice, one giant leap for GWAS?
Mark A Herman, Jonathan E Campbell, David A D’Alessio
Journal of Clinical Investigation
Glucagon lowers glycemia when β cells are active
Megan E Capozzi, Jacob B Wait, Andrew N Gordon Jepchumba Koech, Reilly W Coch, Berit Svendsen, Brian Finan, David A D’Alessio, Jonathan E Campbell
JCI Insight
Intra-Islet Ghrelin Signaling does not Regulate Insulin Secretion from Adult Mice
Sarah M Gray, Jingjing Niu, Amanda Zhang, Berit Svendsen, Jonathan E Campbell, David A D’Alessio, Jenny Tong
Diabetes
Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes
Brian Finan, Megan E Capozzi, Jonathan E Campbell
Diabetes
Marzieh Salehi, Amalia Gastaldelli, David A D'Alessio
Diabetes, Obesity, and Metabolism
Reg3 Proteins as Gut Hormones? Don’t Be Hasty
Jonathan D Douros, Jonathan E Campbell
Endocrinology
Jacqueline L Beaudry, Kiran Deep Kaur, Elodie M Varin, Laurie L Baggio, Xiemin Cao, Erin E Mulvihill, Jennifer H Stern, Jonathan E Campbell, Phillip E Scherer, Daniel J Drucker
Molecular Metabolism
Sleeve gastrectomy rapidly enhances islet function independently of body weight
Jonathan D Douros, Jingjing Niu, Sophia Sdao, Trillian Gregg, Kelsey Fisher-Wellman, Manish Bharadwaj, Anthony Molina, Ramamani Arumugam, MacKenzie Martin, Enrico Petretto, Matthew J Merrins, Mark A Herman, Jenny Tong, Jonathan E Campbell, David A D’Alessio
JCI Insight
Beta Cell tone is defined by proglucagon peptides through cAMP signaling
Megan E Capozzi, Berit Svendsen, Sara E Encisco, Sophie L Lewandowski, Mackenzie D Martin, Haopeng Lin, Justin L Jaffe, Reilly W Coch, Jonathan M Haldeman, Patrick E MacDonald, Matthew J Merrins, David A D’Alessio, Jonathan E Campbell
JCI Insight
Elodie M Varin, Erin E Mulvihill, Jacqueline L Beaudry, Gemma Pujadas, Shai Fuchs, Jean-François Tanti, Sofia Fazio, Kirandeep Kaur, Xiemin Cao, Laurie L Baggio, Dianne Matthews, Jonathan E Campbell, Daniel J Drucker
Cell Metabolism
2018
Melanie J Davies, David A D'Alessio, Judith Fradkin, Walter N Kernan, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Apostolos Tsapas, Deborah J Wexler, John B Buse
Diabetologia
Melanie J Davies, David A D'Alessio, Judith Fradkin, Walter N Kernan, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Apostolos Tsapas, Deborah J Wexler, John B Buse
Diabetes
Rami Al Batran, Keshav Gopal, Mackenzie D Martin, Kim L Ho, Malak Almutairi, Hanin Aburasayn, Farah Eaton, Jonathan E Campbell, John R Ussher
Diabetologia
Tamer Coskun, Kyle W Sloop, Corina Loghin, Jorge Alsina-Fernandex, Shweta Urva, Krister B Bokvist, Xuewei Cui, Daniel A Briere, Over Cabrera, William C Roell, Uma Juchibholta, Julie S Moyers, Charles T Benson, Ruth E Gimeno, David A D'Alessio, Axel Haupt
Molecular Metabolism
Interaction of GLP-1 and Ghrelin on Glucose Tolerance in Healthy Humans
Laura C Page, Amalia Gastaldelli, Sarah M Gray, David A D'Alessio, Jenny Tong
Diabetes
Jonathan D Douros, Alfor G Lewis, Eric P Smith, JingJing Niu, Megan Capozzi, April Wittmann, Jonathan Campbell, Jenny Tong, Constance Wagner, Parinaz Mahbod, Randy Seeley, David A D’Alessio
Diabetes
Can we RISE to the Challenge of Youth-Onset Type 2 Diabetes?
John B Buse, David A D'Alessio, Matthew C Riddell
Diabetes Care
Brett S Peterson, Jonathan E Campbell, Olga Ilkayeva, Paul A Grimsrud, Matthew D Hirschey, Christopher B Newgard
Cell Reports
Targeting the incretin/glucagon system with triagonists to treat diabetes
Megan E Capozzi, Richard D DiMarchi, Matthias H Tschöp, Brian Finan, Jonathan E Campbell
Endocrine Reviews
John R Ussher, Jonathan E Campbell, Erin E Mulvihill, Laurie L Baggio, Holly E Bates, Brent A McLean, Keshav Gopal, Megan Capozzi, Bernardo Yusta, Xiemin Cao, Safina Ali, Minsuk Kim, M Golam Kabir, Yutaka Seino, Jinya Suzuki, Daniel J Drucker
Cell Metabolism
2017
Metformin Use May Moderate the Effect of DPP-4 Inhibitors on Cardiovascular Outcomes
Matthew J Crowley, John W Williams, Andrzej S Kosinski, David A D'Alessio, John B Buse
Diabetes Care
β-cell inactivation of GPR119 unmasks incretin dependence of GPR119-mediated glucoregulation
Brandon L Panaro, Grace B Flock, Jonathan E Campbell, Jacqueline L Beaudry, Xiemin Cao, Daniel J Drucker
Diabetes
SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion
Kristin A Anderson, Frank K Huynh, Kelsey Fisher-Wellman, J Darren Stuart, Brett S Peterson, Jonathan D Douros, Gregory R Wagner, J Will Thompson, Andreas S Madsen, Michelle F Green, R Michael Sivley, Olga R Ilkayeva, Robert D Stevens, Donald S Backos, John A Capra, Christian A Olsen, Jonathan E Campbell, Deborah M Muoio, Paul A Grimsrud, Matthew D Hirschey
Cell Metabolism
DREADDing proglucagon neurons: a fresh look at metabolic regulation by the brain
Jonathan E Campbell, David A D’Alessio
Journal of Clinical Investigation
Sriparna Ghosal, Amy EB Packard, Parinaz Mahbod, Jessica M McKlveen, Randy J Seeley, Brent Myers, Yvonne Ulrich-Lai, Eric P Smith, David A D'Alessio, James P Herman
Journal of Neuroscience
Erin E Mulvihill, Elodie M Varin, Bojana Gladanac, Jonathan E Campbell, John R Ussher, Laurie L Baggio, Bernardo Yusta, Jennifer Ayala, Melissa A Burmeister, Dianne Matthews, KW Annie Bang, Julio E Ayala, Daniel J Drucker
Cell Metabolism
2016
Incretin-based therapies for the failing heart
John R Ussher, Jonathan E Campbell
Cardiovascular Endocrinology & Metabolism
Mechanisms of surgical control of type 2 diabetes: GLP-1 is the key factor - Maybe
Marzieh Salehi, David A D'Alessio
Surgery for Obesity and Related Disease
Erin E Mulvihill, Elodie M Varin, John R Ussher, Jonathan E Campbell, KW Annie Bang, Tahmid Abdullah, Laurie L Baggio, Daniel J Drucker
Diabetes
Bariatric/metabolic surgery for diabetes: Incorporating a powerful treatment into standard care
Bruce M Wolfe, David A D'Alessio
Obesity
TCF1 links GIPR signaling to the control of beta cell function and survival
Jonathan E Campbell, John R Ussher, Erin E Mulvihill, Jelena Kolic, Laurie L Baggio, Xiemen Cao, Yu Liu, Benjamin J Lamont, Tsukasa Morii, Catherine J Streutker, Natalia Tamarina, Louis H Philipson, Jeffrey L Wrana, Patrick E MacDonald, Daniel J Drucker
Nature Medicine
The incretin effect in obese adolescents with and without type 2 diabetes: impaired or intact?
Benedikt A Aulinger, Torsten P Vahl, Ron L Prigeon, David A D'Alessio, Deborah A Elder
American Journal of Physiology Endocrinology and Metabolism
2015
Roger D Gibb, Johnson W McRorie, Darrel A Russell, Vic Hasselblad, David A D'Alessio
Amercial Journal of Clincial Nutrition
Thomas H Inge, Ronald L Prigeon, Deborah A Elder, Todd M Jenkins, Robert M Cohen, Stavra A Xanthakos, Stephen C Benoit, Lawrence M Dolan, Stephen R Daniels, David A D'Alessio
Journal of Pediatrics
Daniel Oropeza, Nathalie Jouvet, Lionel Budry, Jonathan E Campbell, Khalil Bouyakdan, Julie Lacombe, Gabrielle Perron, Valerie Bergeron, Joshua C Neuman, Harpreet K Brar, Rachel J Fenske, Clemence Meunier, Sarah Sczelecki, Michelle E Kimple, Daniel J Drucker, Robert A Screaton, Vincent Poitout, Mathieu Ferron, Thierry Alquier, Jennifer L Estall
Diabetes
Islet α cells and glucagon—critical regulators of energy homeostasis
Jonathan E Campbell, Daniel J Drucker
Nature Reviews Endocrinology
Denovan P Begg, Aaron A May, Joram D Mul, Min Liu, David A D'Alessio, Randy J Seeley, Stephen C Woods
Diabetes
Glucagon-like peptide-1 receptor agonists increase pancreatic mass by induction of protein synthesis
Jacqueline A Koehler, Laurie L Baggio, Xiemin Cao, Tahmid Abdulla, Jonathan E Campbell, Thomas Secher, Jacob Jelsing, Brett Larsen, Daniel J Drucker
Diabetes
Diet-induced obese mice retain endogenous leptin action
Nickki Ottaway, Parinaz Mahbod, Belen Rivero, Lee Ann Norman, Arieh Gertler, David A D'Alessio, Diego Perez-Tilve
Cell Metabolism
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
Brian Finan, Bin Yang, Nickki Ottaway, David L Smiley, Tao Ma, Christoffer Clemmensen, Joe Chabenne, Lianshan Zhang, Kirk M Habegger, Katrin Fischer, Jonathan E Campbell, Darleen Sandoval, Randy J Seeley, Konrad Bleicher, Sabine Uhles, William Riboulet, Jürgen Funk, Cornelia Hertel, Sara Belli, Elena Sebokova, Karin Conde-Knape, Anish Konkar, Daniel J Drucker, Vasily Gelfanov, Paul T Pfluger, Timo D Müller, Diego Perez-Tilve, Richard D DiMarchi, Matthias H Tschöp
Nature Medicine
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