Publications since 2015. DMPI-Endo members in Bold.
2022
73.
The GIPR is predominantly localized to non-adipocyte cell types within white adipose tissue.
Jonathan E. Campbell, Jacquline L. Beaudry, Berit Svendsen, Laurie L. Baggio, Andrew N. Gordon, John R. Ussher, Chi Kin Wong, Fiona M. Gribble, David A. D'Alessio, Frank Reimann, Daniel J. Drucker.
Diabetes
2021
72.
GIP mediates the incretin effect and glucose tolerance by dual actions on alpha cells and beta cells
Kimberley El, Sarah M. Gray, Megan E. Capozzi, Emily R. Knuth, Erli Jin, Berit Svendsen, Alexis Clifford, Jennifer L. Brown, Bryanna M. Chazotte, Kyle W. Sloop, Derek J. Nunez, Matthew J. Merrins, David A. D'Alessio, Jonathan E. Campbell
Science Advances
71.
Extreme elevations of low-density lipoprotein cholesterol with very low carbohydrate, high fat diets
Schaffer AE, D'Alessio DA, Guyton JR.
J Clin Lipidol
70.
Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes
Alonge KM, D'Alessio DA, Schwartz MW
Diabetologia
69.
Mechanisms controlling pancreatic islet cell function in insulin secretion
Jonathan E. Campbell, Christopher B. Newgard
Nature Reviews Molecular Cell Biology
2020
68.
Revisiting the complexity of GLP-1 action - from sites of synthesis to receptor activation
Brent A. McLean, Chi Kin Wong, Jonathan E. Campbell, David J. Hodson, Stefan Trapp, Daniel J. Drucker
Endocrine Reviews
67.
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion
Guo-Fang Zhang, Mette V. Jensen, Sarah M. Gray, Kimberley El, You Wang, Danhong Lu, Thomas C. Becker, Jonathan E. Campbell, Christopher B. Newgard
Cell Metabolism
66.
Targeting the GIPR for obesity: To agonize or antagonize? Potential mechanisms
Jonathan E. Campbell
Molecular Metabolism
65.
Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway
Sophie L. Lewandowski, Rebecca L. Cardone, Hannah R. Foster, Thuong Ho, Evgeniy Potapenko, Chetan Poudel, Halena R. VanDeusen, Sophia M. Sdao, Tiago C. Alves, Xiaojian Zhao, Megan E. Capozzi, Arnaldo H. de Souza, Ishrat Jahan, Craig J. Thomas, Craig S. Nunemaker, Dawn B. Davis, Jonathan E. Campbell, Richard G. Kibbey, Matthew J. Merrins
Cell Metabolism
64.
Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes
Kimberly M. Alonge, David A D'Alessio, Michael W. Schwartz
Diabetologia
63.
Repositioning the alpha cell in postprandial metabolism
Kimberley El, Megan E. Capozzi, Jonathan E. Campbell
Endocrinology
62.
Frank K. Huynh, Brett S. Peterson, Kristin A. Anderson, Zhihong Lin, Aeowynn J. Coakley, Fiara M.S. Llaguno, Thi-Tina N. Nguyen, Jonathan E. Campbell, Samuel B. Stephens, Christopher B. Newgard, Matthew D. Hirschey
American Journal of Physiology: Endocrinology and Metabolism
61.
Caslin A. Gilroy, Megan E. Capozzi, Anastasia K. Varanko, Jenny Tong, David A. D'Alessio, Jonathan E. Campbell, Ashutosh Chilkoti
Science Advances
60.
Could micro changes in beta-cells enable major changes in metabolism?
Megan E. Capozzi, Jonathan E. Campbell
EBioMedicine
59.
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Francis S. Willard, Jonathan D. Douros, Maria B.N. Gabe, Aaron D. Showalter, David B. Wainscott, Todd M. Suter, Megan E. Capozzi, Wijnand J.C. van der Velden, Cynthia Stutsman, Guemalli R. Cardona, Shweta Urva, Paul J. Emmerson, Jens J. Holst, David A. D'Alessio, Matthew P. Coghlan, Mette M. Rosenkilde, Jonathan E. Campbell, Kyle W. Sloop
JCI Insight
58.
Ranee Chatterjee, Clementine A. Davenport, Lydia Kwee, David D'Alessio, Laura P. Svetkey, Pao-Hwa Lin, Cris A. Slentz, Olga Ilkayeva, Johanna Johnson, David Edelman, Svati H Shah
Metabolomics
57.
Bonnie Brehm, Suzanne Summer, Todd Jenkins, David D'Alessio, Thomas Inge
Surgery for Obesity and Related Disorders
56.
Jeremy H. Pettus, David A D'Alessio, Juan P. Frias, Eric G. Vajda, James D. Pipkin, Julio Rosenstock, Gretchen Williamson, Miriam A. Zangmeister, Lin Zhi, Keith B. Marschke
Diabetes Care
55.
Discordance between GLP-1R gene and protein expression in mouse pancreatic islets cells
Sarah M. Gray, Yurong Xin, Elizabeth C. Ross, Bryanna M. Chazotte, Megan E. Capozzi, Kimberley El, Berit Svendsen, Peter Ravn, Kyle W. Sloop, Jenny Tong, Jesper Gromada, Jonathan E. Campbell, David A. D'Alessio
Journal of Biological Chemistry
54.
Rami Al Batran, Keshav Goal, Megan E. Capozzi, Jadin J. Chahade, Bruno Saleme, S. Amirhossein Tabatabaei-Dakhili, Amada A. Greenwell, Jingjing Nui, Malak Almutairi, Nikole J. Myme, Grant Masson, Ryekjang Kim, Carlos A. Velazquez-Martinez, Celine Agues, Peter A. Crawford, Gopinath Sutendra, Jonathan E. Campbell, Jason R.B. Dyck, John R. Ussher.
Cell Metabolism
53.
The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition
Megan E. Capozzi, Reilly W. Coch, Jepchumba Koech, Inna I. Astapova, Jacob B. Wait, Sara E. Encisco, Jonathan D. Douros, Kimberly El, Brian Finan, Kyle W. Sloop, Mark A. Herman, David A. D’Alessio, Jonathan E. Campbell
Diabetes
2019
52.
John B Buse, Deborah J Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A D'Alessio, Melanie J Davies
Diabetes Care
51.
John B Buse, Deborah J Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A D'Alessio, Melanie J Davies
Diabetologia
50.
Pharmacological Antagonism of the Incretin System Protects Against Diet-induced Obesity.
Berit Svendsen, Megan E Capozzi, Jingjing Nui, Sarah A Hannou, Brian Finan, Jacqueline Naylor, Peter Ravn, David A D’Alessio, Jonathan E Campbell.
Molecular Metabolism
49.
Rapid hepatic metabolism blunts the endocrine actions of portally infused GLP-1 in male rats.
Benedikt A Aulinger, Marta Perabo, Randy J Seeley, Klaus G Parhofer, David A D'Alessio
American Journal of Physiology Endocrinology and Metabolism
48.
The effects of preioperative dexamethasone on glycemic control and postoperative outcomes.
Rebecca A Herbst, Onala T Telford, John Hunting, W Michael Bullock, Erin Manning, Beatrics D Hong, David A D'Alessio, Tracy L Setji
Endocrine Practice
47.
L-citrulline supplementation improvew glucose and exercise tolerance in obese male mice
Amina Eshreif, Rami Al Batran, K Lockhart Jamieson, Ahmed M Darwesh, Keshav Gopal, Amanda A Greenwell, Igor Zlobine, Hanin Aburasayn, Farah Eaton, Erin E Mulvihill, Jonathan E Campbell, John M Seubert, John R Ussher
Experimental Physiology
46.
45.
Physiological roles of the GIP receptor in murine brown adipose tissue
Jacqueline L Beaudry, Kiran D Kaur, Elodie M Varin, Laurie L Baggio, Xiemin Cao, Erin E Mulvihill, Holly E Bates, Jonathan E Campbell, Daniel J Drucker
Molecular Metabolism
44.
The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control
Jonathan D Douros, Jenny Tony, David A D'Alessio
Endocrine Reviews
43.
Jonathan D Douros, Jingjing Niu, Sophia Sdao, Trillian Gregg, Matthew J Merrins, Jonathan Campbell, Jenny Tong, David D'Alessio
Molecular Metabolism
42.
The role of GIP and pancreatic GLP-1 in the glucoregulatory effect of DPP-4 inhibition in mice.
Chelsea R. Hutch, Karen Roelofs, April Haller, Joyce Sorrell, Kyle Leix, David A. D'Alessio, Robert Augustin, Randy J. Seeley, Thomas Klein, Darleen A. Sandoval
Diabetologia
41.
Beta-cell sensitivity to insulinotropic gut hormones is reduced after gastric bypass surgery
Marzieh Salehi, Amalia Gastaldelli, David A D'Alessio
Gut
40.
One small step for mice, one giant leap for GWAS?
Mark A Herman, Jonathan E Campbell, David A D’Alessio
Journal of Clinical Investigation
39.
Glucagon lowers glycemia when β cells are active
Megan E Capozzi, Jacob B Wait, Andrew N Gordon Jepchumba Koech, Reilly W Coch, Berit Svendsen, Brian Finan, David A D’Alessio, Jonathan E Campbell
JCI Insight
38.
Intra-Islet Ghrelin Signaling does not Regulate Insulin Secretion from Adult Mice
Sarah M Gray, Jingjing Niu, Amanda Zhang, Berit Svendsen, Jonathan E Campbell, David A D’Alessio, Jenny Tong
Diabetes
37.
Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes
Brian Finan, Megan E Capozzi, Jonathan E Campbell
Diabetes
36.
Marzieh Salehi, Amalia Gastaldelli, David A D'Alessio
Diabetes, Obesity, and Metabolism
35.
Reg3 Proteins as Gut Hormones? Don’t Be Hasty
Jonathan D Douros, Jonathan E Campbell
Endocrinology
34.
Jacqueline L Beaudry, Kiran Deep Kaur, Elodie M Varin, Laurie L Baggio, Xiemin Cao, Erin E Mulvihill, Jennifer H Stern, Jonathan E Campbell, Phillip E Scherer, Daniel J Drucker
Molecular Metabolism
33.
Sleeve gastrectomy rapidly enhances islet function independently of body weight
Jonathan D Douros, Jingjing Niu, Sophia Sdao, Trillian Gregg, Kelsey Fisher-Wellman, Manish Bharadwaj, Anthony Molina, Ramamani Arumugam, MacKenzie Martin, Enrico Petretto, Matthew J Merrins, Mark A Herman, Jenny Tong, Jonathan E Campbell, David A D’Alessio
JCI Insight
32.
Beta Cell tone is defined by proglucagon peptides through cAMP signaling
Megan E Capozzi, Berit Svendsen, Sara E Encisco, Sophie L Lewandowski, Mackenzie D Martin, Haopeng Lin, Justin L Jaffe, Reilly W Coch, Jonathan M Haldeman, Patrick E MacDonald, Matthew J Merrins, David A D’Alessio, Jonathan E Campbell
JCI Insight
31.
Elodie M Varin, Erin E Mulvihill, Jacqueline L Beaudry, Gemma Pujadas, Shai Fuchs, Jean-François Tanti, Sofia Fazio, Kirandeep Kaur, Xiemin Cao, Laurie L Baggio, Dianne Matthews, Jonathan E Campbell, Daniel J Drucker
Cell Metabolism
2018
30.
Melanie J Davies, David A D'Alessio, Judith Fradkin, Walter N Kernan, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Apostolos Tsapas, Deborah J Wexler, John B Buse
Diabetologia
29.
Melanie J Davies, David A D'Alessio, Judith Fradkin, Walter N Kernan, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Apostolos Tsapas, Deborah J Wexler, John B Buse
Diabetes
28.
Rami Al Batran, Keshav Gopal, Mackenzie D Martin, Kim L Ho, Malak Almutairi, Hanin Aburasayn, Farah Eaton, Jonathan E Campbell, John R Ussher
Diabetologia
27.
Tamer Coskun, Kyle W Sloop, Corina Loghin, Jorge Alsina-Fernandex, Shweta Urva, Krister B Bokvist, Xuewei Cui, Daniel A Briere, Over Cabrera, William C Roell, Uma Juchibholta, Julie S Moyers, Charles T Benson, Ruth E Gimeno, David A D'Alessio, Axel Haupt
Molecular Metabolism
26.
Interaction of GLP-1 and Ghrelin on Glucose Tolerance in Healthy Humans
Laura C Page, Amalia Gastaldelli, Sarah M Gray, David A D'Alessio, Jenny Tong
Diabetes
25.
Jonathan D Douros, Alfor G Lewis, Eric P Smith, JingJing Niu, Megan Capozzi, April Wittmann, Jonathan Campbell, Jenny Tong, Constance Wagner, Parinaz Mahbod, Randy Seeley, David A D’Alessio
Diabetes
24.
Can we RISE to the Challenge of Youth-Onset Type 2 Diabetes?
John B Buse, David A D'Alessio, Matthew C Riddell
Diabetes Care
23.
Brett S Peterson, Jonathan E Campbell, Olga Ilkayeva, Paul A Grimsrud, Matthew D Hirschey, Christopher B Newgard
Cell Reports
22.
Targeting the incretin/glucagon system with triagonists to treat diabetes
Megan E Capozzi, Richard D DiMarchi, Matthias H Tschöp, Brian Finan, Jonathan E Campbell
Endocrine Reviews
21.
John R Ussher, Jonathan E Campbell, Erin E Mulvihill, Laurie L Baggio, Holly E Bates, Brent A McLean, Keshav Gopal, Megan Capozzi, Bernardo Yusta, Xiemin Cao, Safina Ali, Minsuk Kim, M Golam Kabir, Yutaka Seino, Jinya Suzuki, Daniel J Drucker
Cell Metabolism
2017
20.
Metformin Use May Moderate the Effect of DPP-4 Inhibitors on Cardiovascular Outcomes
Matthew J Crowley, John W Williams, Andrzej S Kosinski, David A D'Alessio, John B Buse
Diabetes Care
19.
β-cell inactivation of GPR119 unmasks incretin dependence of GPR119-mediated glucoregulation
Brandon L Panaro, Grace B Flock, Jonathan E Campbell, Jacqueline L Beaudry, Xiemin Cao, Daniel J Drucker
Diabetes
18.
SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion
Kristin A Anderson, Frank K Huynh, Kelsey Fisher-Wellman, J Darren Stuart, Brett S Peterson, Jonathan D Douros, Gregory R Wagner, J Will Thompson, Andreas S Madsen, Michelle F Green, R Michael Sivley, Olga R Ilkayeva, Robert D Stevens, Donald S Backos, John A Capra, Christian A Olsen, Jonathan E Campbell, Deborah M Muoio, Paul A Grimsrud, Matthew D Hirschey
Cell Metabolism
17.
DREADDing proglucagon neurons: a fresh look at metabolic regulation by the brain
Jonathan E Campbell, David A D’Alessio
Journal of Clinical Investigation
16.
Sriparna Ghosal, Amy EB Packard, Parinaz Mahbod, Jessica M McKlveen, Randy J Seeley, Brent Myers, Yvonne Ulrich-Lai, Eric P Smith, David A D'Alessio, James P Herman
Journal of Neuroscience
15.
Erin E Mulvihill, Elodie M Varin, Bojana Gladanac, Jonathan E Campbell, John R Ussher, Laurie L Baggio, Bernardo Yusta, Jennifer Ayala, Melissa A Burmeister, Dianne Matthews, KW Annie Bang, Julio E Ayala, Daniel J Drucker
Cell Metabolism
2016
14.
Incretin-based therapies for the failing heart
John R Ussher, Jonathan E Campbell
Cardiovascular Endocrinology & Metabolism
13.
Mechanisms of surgical control of type 2 diabetes: GLP-1 is the key factor - Maybe
Marzieh Salehi, David A D'Alessio
Surgery for Obesity and Related Disease
12.
Erin E Mulvihill, Elodie M Varin, John R Ussher, Jonathan E Campbell, KW Annie Bang, Tahmid Abdullah, Laurie L Baggio, Daniel J Drucker
Diabetes
11.
Bariatric/metabolic surgery for diabetes: Incorporating a powerful treatment into standard care
Bruce M Wolfe, David A D'Alessio
Obesity
10.
TCF1 links GIPR signaling to the control of beta cell function and survival
Jonathan E Campbell, John R Ussher, Erin E Mulvihill, Jelena Kolic, Laurie L Baggio, Xiemen Cao, Yu Liu, Benjamin J Lamont, Tsukasa Morii, Catherine J Streutker, Natalia Tamarina, Louis H Philipson, Jeffrey L Wrana, Patrick E MacDonald, Daniel J Drucker
Nature Medicine
9.
The incretin effect in obese adolescents with and without type 2 diabetes: impaired or intact?
Benedikt A Aulinger, Torsten P Vahl, Ron L Prigeon, David A D'Alessio, Deborah A Elder
American Journal of Physiology Endocrinology and Metabolism
2015
8.
Roger D Gibb, Johnson W McRorie, Darrel A Russell, Vic Hasselblad, David A D'Alessio
Amercial Journal of Clincial Nutrition
7.
Thomas H Inge, Ronald L Prigeon, Deborah A Elder, Todd M Jenkins, Robert M Cohen, Stavra A Xanthakos, Stephen C Benoit, Lawrence M Dolan, Stephen R Daniels, David A D'Alessio
Journal of Pediatrics
6.
Daniel Oropeza, Nathalie Jouvet, Lionel Budry, Jonathan E Campbell, Khalil Bouyakdan, Julie Lacombe, Gabrielle Perron, Valerie Bergeron, Joshua C Neuman, Harpreet K Brar, Rachel J Fenske, Clemence Meunier, Sarah Sczelecki, Michelle E Kimple, Daniel J Drucker, Robert A Screaton, Vincent Poitout, Mathieu Ferron, Thierry Alquier, Jennifer L Estall
Diabetes
5.
Islet α cells and glucagon—critical regulators of energy homeostasis
Jonathan E Campbell, Daniel J Drucker
Nature Reviews Endocrinology
4.
Denovan P Begg, Aaron A May, Joram D Mul, Min Liu, David A D'Alessio, Randy J Seeley, Stephen C Woods
Diabetes
3.
Glucagon-like peptide-1 receptor agonists increase pancreatic mass by induction of protein synthesis
Jacqueline A Koehler, Laurie L Baggio, Xiemin Cao, Tahmid Abdulla, Jonathan E Campbell, Thomas Secher, Jacob Jelsing, Brett Larsen, Daniel J Drucker
Diabetes
2.
Diet-induced obese mice retain endogenous leptin action
Nickki Ottaway, Parinaz Mahbod, Belen Rivero, Lee Ann Norman, Arieh Gertler, David A D'Alessio, Diego Perez-Tilve
Cell Metabolism
1.
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
Brian Finan, Bin Yang, Nickki Ottaway, David L Smiley, Tao Ma, Christoffer Clemmensen, Joe Chabenne, Lianshan Zhang, Kirk M Habegger, Katrin Fischer, Jonathan E Campbell, Darleen Sandoval, Randy J Seeley, Konrad Bleicher, Sabine Uhles, William Riboulet, Jürgen Funk, Cornelia Hertel, Sara Belli, Elena Sebokova, Karin Conde-Knape, Anish Konkar, Daniel J Drucker, Vasily Gelfanov, Paul T Pfluger, Timo D Müller, Diego Perez-Tilve, Richard D DiMarchi, Matthias H Tschöp
Nature Medicine
This information is intended to be a resource for members of the DMPI Endocrinology group